diff --git a/src/views/business/form/drug/comp/edit.vue b/src/views/business/form/drug/comp/edit.vue
index 921ef9e..4f90ee1 100644
--- a/src/views/business/form/drug/comp/edit.vue
+++ b/src/views/business/form/drug/comp/edit.vue
@@ -118,7 +118,7 @@ export default {
         if (valid) {
           this.infoDialog.formData.status = status
           if(status === 3){
-            this.$refs.editSignRef.show(this.oldStatus==1?this.$t('page.business.study.drug.submit'):this.$t('page.business.study.drug.xgsy'),this.oldStatus==1?this.$t('page.business.study.drug.create'):this.$t('page.business.study.drug.xgsy'))
+            this.$refs.editSignRef.show(this.oldStatus==1?this.$t('page.business.study.drug.submit'):this.$t('page.business.study.drug.xgsy'),this.oldStatus==1?this.$t('page.business.study.drug.create'):this.$t('page.business.study.drug.xgsy'),false,null,this.oldStatus!=1,this.oldStatus!=1)
           }else{
             this.doSave({})
           }
diff --git a/src/views/business/form/drug/comp/sign.vue b/src/views/business/form/drug/comp/sign.vue
index 97dedfc..e9054be 100644
--- a/src/views/business/form/drug/comp/sign.vue
+++ b/src/views/business/form/drug/comp/sign.vue
@@ -5,7 +5,7 @@
       <el-form ref="signForm" :model="form" :rules="rules" label-width="120px">
         <el-row>
           <el-col :span="24" v-if="showDate">
-            <el-form-item :label="$t('page.business.study.nonTrial.jysj')" prop="startDate">
+            <el-form-item :label="$t('page.business.study.drug.jysj')" prop="startDate">
               <el-date-picker v-model="dateArr" clearable type="daterange" range-separator="-" :start-placeholder="$t('form.startDate')"
             :end-placeholder="$t('form.endDate')" value-format="yyyy-MM-dd" style="width: 100%" @change="changeDate" />
             </el-form-item>
@@ -18,7 +18,7 @@
             </el-form-item>
           </el-col>
           <el-col :span="24">
-            <el-form-item :label="$t('form.remark')" prop="remark">
+            <el-form-item :label="isReson?$t('form.reason'):$t('form.remark')" prop="remark">
               <el-input type="textarea" v-model="form.remark" :rows="2" maxlength="500"
                 :placeholder="$t('form.placeholderInput')">
               </el-input>
@@ -89,7 +89,9 @@ export default {
           message: ' ',
           trigger: 'change'
         }]
-      }
+      },
+
+      isReson:false
     }
   },
   computed: {
@@ -97,9 +99,9 @@ export default {
   created() {
   },
   methods: {
-    show(title,qmyy,showDate) {
+    show(title,qmyy,showDate,selectedDate,isReson,reasonRequired) {
       this.showDate = showDate==undefined?false:showDate
-      this.dateArr = []
+      this.dateArr = selectedDate || []
       this.title = title
       this.form = {
         qmyy:qmyy,
@@ -108,11 +110,45 @@ export default {
         qmrMc:this.$store.getters.nickName,
         qmrMcEn:this.$store.getters.name,
         qmrmm:'',
-        startDate:'',
-        endDate:''
+        startDate:selectedDate&&selectedDate.length>0?selectedDate[0]:'',
+        endDate:selectedDate&&selectedDate.length>1?selectedDate[1]:''
       }
       this.resetForm("signForm")
       this.open = true
+
+      this.isReson = isReson || false
+      if(reasonRequired){
+        this.rules ={
+          qmrmm: [{
+            required: true,
+            message: ' ',
+            trigger: 'blur'
+          }],
+          startDate: [{
+            required: true,
+            message: ' ',
+            trigger: 'change'
+          }],
+          remark: [{
+            required: true,
+            message: ' ',
+            trigger: 'blur'
+          }]
+        }
+      }else{
+        this.rules ={
+          qmrmm: [{
+            required: true,
+            message: ' ',
+            trigger: 'blur'
+          }],
+          startDate: [{
+            required: true,
+            message: ' ',
+            trigger: 'change'
+          }]
+        }
+      }
     },
     cancel() {
       this.open = false
diff --git a/src/views/business/form/nonTrial/comp/edit.vue b/src/views/business/form/nonTrial/comp/edit.vue
index 4939b91..36927b3 100644
--- a/src/views/business/form/nonTrial/comp/edit.vue
+++ b/src/views/business/form/nonTrial/comp/edit.vue
@@ -118,7 +118,7 @@ export default {
         if (valid) {
           this.infoDialog.formData.status = status
           if(status === 3){
-            this.$refs.editSignRef.show(this.oldStatus==1?this.$t('page.business.study.nonTrial.submit'):this.$t('page.business.study.nonTrial.xgsy'),this.oldStatus==1?this.$t('page.business.study.nonTrial.create'):this.$t('page.business.study.nonTrial.xgsy'))
+            this.$refs.editSignRef.show(this.oldStatus==1?this.$t('page.business.study.nonTrial.submit'):this.$t('page.business.study.nonTrial.xgsy'),this.oldStatus==1?this.$t('page.business.study.nonTrial.create'):this.$t('page.business.study.nonTrial.xgsy'),false,null,this.oldStatus!=1,this.oldStatus!=1)
           }else{
             this.doSave({})
           }
diff --git a/src/views/business/form/nonTrial/comp/sign.vue b/src/views/business/form/nonTrial/comp/sign.vue
index 9357bfc..e9054be 100644
--- a/src/views/business/form/nonTrial/comp/sign.vue
+++ b/src/views/business/form/nonTrial/comp/sign.vue
@@ -18,7 +18,7 @@
             </el-form-item>
           </el-col>
           <el-col :span="24">
-            <el-form-item :label="$t('form.remark')" prop="remark">
+            <el-form-item :label="isReson?$t('form.reason'):$t('form.remark')" prop="remark">
               <el-input type="textarea" v-model="form.remark" :rows="2" maxlength="500"
                 :placeholder="$t('form.placeholderInput')">
               </el-input>
@@ -89,7 +89,9 @@ export default {
           message: ' ',
           trigger: 'change'
         }]
-      }
+      },
+
+      isReson:false
     }
   },
   computed: {
@@ -97,9 +99,9 @@ export default {
   created() {
   },
   methods: {
-    show(title,qmyy,showDate) {
+    show(title,qmyy,showDate,selectedDate,isReson,reasonRequired) {
       this.showDate = showDate==undefined?false:showDate
-      this.dateArr = []
+      this.dateArr = selectedDate || []
       this.title = title
       this.form = {
         qmyy:qmyy,
@@ -108,11 +110,45 @@ export default {
         qmrMc:this.$store.getters.nickName,
         qmrMcEn:this.$store.getters.name,
         qmrmm:'',
-        startDate:'',
-        endDate:''
+        startDate:selectedDate&&selectedDate.length>0?selectedDate[0]:'',
+        endDate:selectedDate&&selectedDate.length>1?selectedDate[1]:''
       }
       this.resetForm("signForm")
       this.open = true
+
+      this.isReson = isReson || false
+      if(reasonRequired){
+        this.rules ={
+          qmrmm: [{
+            required: true,
+            message: ' ',
+            trigger: 'blur'
+          }],
+          startDate: [{
+            required: true,
+            message: ' ',
+            trigger: 'change'
+          }],
+          remark: [{
+            required: true,
+            message: ' ',
+            trigger: 'blur'
+          }]
+        }
+      }else{
+        this.rules ={
+          qmrmm: [{
+            required: true,
+            message: ' ',
+            trigger: 'blur'
+          }],
+          startDate: [{
+            required: true,
+            message: ' ',
+            trigger: 'change'
+          }]
+        }
+      }
     },
     cancel() {
       this.open = false
diff --git a/src/views/business/study/comp/edit.vue b/src/views/business/study/comp/edit.vue
index 1234ecd..39969d8 100644
--- a/src/views/business/study/comp/edit.vue
+++ b/src/views/business/study/comp/edit.vue
@@ -118,7 +118,7 @@ export default {
         if (valid) {
           this.infoDialog.formData.status = status
           if(status === 3){
-            this.$refs.editSignRef.show(this.oldStatus==1?this.$t('page.business.study.study.submit'):this.$t('page.business.study.study.xgsy'),this.oldStatus==1?this.$t('page.business.study.study.create'):this.$t('page.business.study.study.xgsy'))
+            this.$refs.editSignRef.show(this.oldStatus==1?this.$t('page.business.study.study.submit'):this.$t('page.business.study.study.xgsy'),this.oldStatus==1?this.$t('page.business.study.study.create'):this.$t('page.business.study.study.xgsy'),false,null,this.oldStatus!=1,this.oldStatus!=1)
           }else{
             this.doSave({})
           }